| Although a number of medications
are now available to treat fibromyalgia, two drugs, amitriptyline (Elavil)
and cyclobenzaprine (Flexeril) remain quite popular and are helpful to
many patients. Both have the advantage of having undergone extensive clinical
testing for effectiveness in the treatment of fibromyalgia. Although prescribed
for the treatment of depression in much higher dosages, the tricyclic
antidepressant amitriptyline is often useful in low doses to fibromyalgia
patients because it addresses the serotonin deficiency which often accompanies
FM and helps control pain and promote sleep. The medication cyclobenzaprine
is a muscle relaxant which has proved helpful in the treatment of FM muscle
pain and spasm. Both drugs are usually taken at bedtime, or earlier in
the evening if they produce a "hangover" effect the next day.
For those patients who do not tolerate these drugs well, many other similar-acting
medications are available (i.e., doxepin, nortriptyline, trazadone, etc.).
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